Department of Bioorganic Medicinal Chemistry
Department
Professor | Masami Ohtsuka motsuka(at mark)gpo.kumamoto-u.ac.jp |
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Assistant Professor | Yoshinari Okamoto okamoto(at mark)gpo.kumamoto-u.ac.jp |
Research themes
[Names and Summaries of Research Projects]
- Research in Synthesis of Artificial and Natural Bioactive Compounds
- Design, Synthesis, and Functional Analysis of Inositol Phosphate Derivatives that Target PH Domain Proteins and IP3 Receptors
- Design, Synthesis, and Functional Analysis of Artificial Compounds that Target Zinc-Containing Proteins
- Design, Synthesis, and Functional Analysis of New Metal Chelators
- Design, Synthesis, and Functional Analysis of Compounds to Inhibit the Functionality of Transcription Factor NF-kB
- Design, Synthesis, and Functional Analysis of Medicine that Targets the Brain
- Academic Research of the HIV Molecular Virus
- Creation of HIV-1 Gag-Targeting Inhibitors
- Creation of Anti-HIV Host Factor-Controlling Compounds
- Functional Analysis of HIV Vpr/Vpx
At our department, we conduct design, synthesis, and functional analysis of chemical compounds with bioactive properties such as the following:
- Synthesis and Design of Inositol Phosphate Derivatives and Other Artificial Compounds Active in Intracellular Signal Transduction
- Design and Synthesis of Cancer-Fighting Drugs Targeting Various Molecules Such as Zinc-Containing Protease or Transcription Factor NFkB
- Design and Synthesis of New DNA Cutting Artificial Compounds
- Design and Synthesis of Medicine Targeting the Brain
- Academic Research of the HIV Molecular Virus Related to HIV-1 Vif Proteins
- Elucidation of Mechanisms of Replication Control of HIV and Creation of Related HIV Inhibitors