Departments

Department

Research themes

[Names and Summaries of Research Projects]

• Research of Development of Highly Versatile Synthesis Methods of Basic Chiral Molecules Found in Medical Product Structures
  1. Chiral Synthesis Using 2-Amino Alcohol-Based Compounds of 2-Oxazolone as a Constructing Agent
  2. Chiral Synthesis Using 1,2-Diamine-Based Compounds of 2-Imidazolone as a Constructing Agent
• Research in the Design of Chiral Reaction Fields Using Constrained Conformation Synthesis
  1. Development and Application of New 2-Amino Alcohol-Based Asymmetric Adjuvants
  2. Development and Application of New 1,2-Diamine-Based Asymmetric Adjuvants
  3. Development of Asymmetric Synthesis Reactions Utilizing Symmetry Breaking

There are a huge amount of optically active compounds all around us. In the living world, chirality carries a crucial connotation, and chiral bioactive substances, which have 100% optical purity, are in high demand in fields such as medicine. At our department, we seek to develop highly asymmetrical controlled reactions and efficient chiral compound synthesis of polyfunctional bioactive substances using simple heterocyclic five-membered ring compounds. Namely, we have developed our own chiral synthesis method using highly asymmetric, multi-purpose chiral compounds, and have made strides in the research and development of unique "roofed" asymmetric spaces in chemical structures to produce highly asymmetrical controlled reactions. Building off of this expertise, we are currently eagerly investigating a new, even more practical asymmetric control method.

[Fullsize Image]