発表論文 - 2025年
- Hamdy AK, Araki H, Tateishi H, Toma T, Radwan MO, Biswas S, Kuwata T, Matsushita S, Fujita M, Niwa S, and Otsuka M.
Synthesis of a 5,6-dihydropyran-2-one derivative with dual anti-cell migration and anticancer activity.
Synlett, in press.
- Ciftci H, Oral A, Coskun Y, Renda G, Otsuka M, Fujita M, and Sever B.
Assessment of the anticancer function of Coronilla orientalis MILLER through comprehensive in vitro and computational studies.
Turkish Journal of Biochemistry, in press.
- Irgit A, Kamis R, Sever B, Tuyun AF, Otsuka M, Fujita M, Demirci H, and Ciftci H.
Structure and dynamics of the ABL1 tyrosine kinase and its important role in chronic myeloid leukemia.
Archiv der Pharmazie, in press.
- Yilmaz M, Sever B, Kutlu Y, Gul M, Okuducu C, Tavli S, Otsuka M, Fujita M, Haliloglu T, Ciftci H, and DeMirci H.
Insights into therapeutic discovery through the Kelch domain structure of Keap1 at ambient temperature.
Turkish Journal of Biology, in press.
- Duzgun E, Buyukgungor A, Cigdem M, Gura S, Sever B, Otsuka M, Fujita M, Demirci H, and Ciftci H.
A structural insight into two important ErbB receptors (EGFR and HER2) and their relevance to non-small cell lung cancer.
Archiv der Pharmazie 358: e2400992, 2025.
- Reymova F, Sever B, Topalan E, Sevimli-Gur C, Can M, Tuyun AF, Basoglu F, Ece A, Otsuka M, Fujita M, Demirci H, and Ciftci H.
Design, synthesis and mechanistic anticancer evaluation of new pyrimidine-tethered compounds.
Pharmaceuticals 18: 270, 2025.
- Toma T, Nakahara R, Otsuka M, Fujita M, and Tateishi H.
An anti-cell migration compound that binds to hnRNP U and suppresses nuclear deformation.
Bioorganic Chemistry 156: 108215, 2025.
- Sakamoto M, Kai S, Tateishi H, Biswas T, Sakamoto T, Teshima M, Iwanaga M, Nishikawa A, Sakamoto A, Shimozono R, Kameyama H, Nambu M, Masunaga T, Anraku K, Fujita M, and Otsuka M.
Oxaprozin and SB-431542 hybrid molecule inhibits fibrosis and cancer cell migration.
Synlett, in press.
- Ichimaru Y, Kato K, Yamaguchi Y, Sakamoto T, Jin W, Kurihara M, Fujita M, Otsuka M, and Kurosaki H.
Design, synthesis and characterization of 1-(anthracen-9-ylmethyl)-1,5,9 triazacyclododecane (ant-[12]aneN3) and its DNA photocleavage activity.
Chemical and Pharmaceutical Bulletin 73: 103-108, 2025.
