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研究紹介

発表論文 - 2010年

  1. Nomaguchi M, Doi N, Fujiwara S, Fujita M, and Adachi A.
    Site-directed mutagenesis of HIV-1 vpu gene demonstrates two clusters of replication-defective mutants with distinct ability to down-regulate cell surface CD4 and tetherin.
    Frontiers in Microbiology 1: 116, 2010.
  2. Anraku K, Fukuda R, Takamune N, Misumi S, Okamoto Y, Otsuka M, and Fujita M.
    Highly sensitive analysis of the interaction between HIV-1 Gag and phosphoinositide derivatives based on surface plasmon resonance.
    Biochemistry 49: 5109-5116, 2010.
  3. Yamakawa N, Suemasu S, Matoyama M, Kimoto A, Takeda M, Tanaka K, Ishihara T, Katsu T, Okamoto Y, Otsuka M, and Mizushima T.
    Properties and synthesis of 2-{2-fluoro (or bromo)-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: non-steroidal anti-inflammatory drugs with low membrane permeabilizing and gastric lesion-producing activities.
    Journal of Medicinal Chemistry 53: 7879-7882, 2010.
  4. Matsuno K, Masuda Y, Uehara Y, Sato H, Muroya A, Takahashi O, Yokotagawa T, Furuya T, Okawara T, Otsuka M, Ogo N, Ashizawa T, Oshita C, Tai S, Ishii H, Akiyama Y, and Asai A.
    Identification of a new series of STAT3 inhibitors by virtual screening.
    ACS Medicinal Chemistry Letters 1: 371-375, 2010.
  5. Yamakawa N, Suemasu S, Kimoto A, Arai Y, Ishihara T, Yokomizo K, Okamoto Y, Otsuka M, Tanaka K, and Mizushima T.
    Low direct cytotoxicity of Loxoprofen on gastric mucosal cells.
    Biological & Pharmaceutical Bulletin 33: 398-403, 2010.
  6. Wei Q, Harada K, Minamoto K, Wei C-N. Okamoto Y, Otsuka M, and Ued A.
    Evaluation of allergenicity of constitutents of myoga using the murine local lymph node assay (LLNA).
    International Journal of Immunopathology & Pharmacology 23: 463-470, 2010.
  7. Fujita M, Otsuka M, Nomaguchi M, and Adachi A.
    Multifaceted activity of HIV Vpr/Vpx proteins: the current view of their virological functions.
    Reviews in Medical Virology 20: 68-76, 2010.
  8. Jere A, Fujita M, Adachi A, and Nomaguchi M.
    Role of HIV-1 Nef protein for virus replication in vitro.
    Microbes and Infection 12: 65-70, 2010.