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研究紹介

発表論文 - 2015年

  1. Karabacak M, Altintop MD, Ciftci HI, Koga R, Otsuka M, Fujita M, and Ozdemir A
    Synthesis and evaluation of new pyrazoline derivatives as potential anticancer agents.
    Molecules 20: 19066-19084, 2015.
  2. Ali TFS, Iwamaru K, Ciftci HI, Koga R, Matsumoto M, Oba Y, Kurosaki H, Fujita M, Okamoto Y, Umezawa K, Nakao M, Hide T, Makino K, Kuratsu J, Abdel-Aziz M, Abuo-Rahma GE-DAA, Beshr EAM, and Otsuka M.
    Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system.
    Bioorganic & Medicinal Chemistry 23: 5476-82, 2015.
  3. Ida S, Iwamaru K, Fujita M, Okamoto Y, Kudo Y, Kurosaki H, and Otsuka M.
    L-Histidyl-glycyl-glycyl-L-histiddine. Amino-acid structuring of the bleomycin-type pentadentate metal-binding environment capable of efficient double-strand cleavage of plasmid DNA.
    Bioorganic Chemistry 62: 8-14, 2015.
  4. Ciftci HI, Fujino H, Koga R, Yamamoto M, Kawamura S, Tateishi H, Iwatani Y, Otsuka M, and Fujita M.
    Mutational analysis of HIV-2 Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD1.
    FEBS Letters 589: 1505-1514, 2015.