Based on analyses of specific interactions of biological molecules, such as proteins and nucleic acids, we are studying aimed at developing functional molecules for drug discovery, pathophysiological study, and therapeutic research by means of protein engineering methods and synthetic small compounds. Our recent research projects are as follows.
(1) Analyses of antigen recognition mechanisms and development of functional recombinant antibody molecules.
(2) Structural and functional analysis of relationships of DNA replication and/or repair proteins.
(3) Elucidation of dynamic feature of tyrosine kinases for development of novel inhibitors.
We conduct researches and provide educations based on knowledge and technology about biochemistry, physical chemistry, analytical chemistry, molecular biology, bioorganic chemistry and bioinorganic chemistry.
MORIOKA Hiroshi Professor
●Specialized field:
Biological System Pharmaceutical Science, Analytical Chemistry, Protein Structure-Function Relationship, Molecular Biology
●Address:
Kumamoto University Faculty of Medical and Pharmaceutical Sciences Department of Analytical and Biophysical Chemistry 5-1 ooe-honncho, kumamoto, 862-0973, Japan
●Tel/Fax:
+81-96-371-4350
●e-mail:
morioka(at)gpo.kumamoto-u.ac.jp