Publications

2025

Hori, Kengo; Kurauchi, Yuki; Kotani, Shunsuke; Devkota, Hari Prasad. Analysis of Functional Compounds in Matcha by Quantitative Nuclear Magnetic Resonance Spectroscopy. Scientia Pharmaceutica 2025, 93, (1), 11. DOI
Sadahiro, Yusaku; Okubo, Misaki; Hitora, Yuki; Hitora-Imamura, Natsuko; Kotani, Shunsuke; Tsukamoto, Sachiko. Pestones A and B from a Fungus Pestalotiopsis sp. Bound to Mutant p53 and Changed Its Conformation. Journal of Natural Products 2025, 88, (2), 546–553. DOI
Sadahiro, Yusaku; Okubo, Misaki; Hitora, Yuki; Hitora-Imamura, Natsuko; Kotani, Shunsuke; Tsukamoto, Sachiko. Correction to Pestones A and B from a Fungus Pestalotiopsis sp. Bound to Mutant p53 and Changed its Conformation. Journal of Natural Products 2025, 88, (7), 1868. DOI
Imai, Teruko; Isasaka, Masanari; Oyama, Yusuke; Takagi, Yusuke; Ohura, Kayoko; Kotani, Shunsuke; Nakadae, Yuichiro. Functional analysis of modified caco-2 cells carrying CES2A1 as a model for intestinal absorption of prodrugs. Biological & Pharmaceutical Bulletin 2025, 48, (2), 162–171. DOI

2024

Kotani, S.; Asano, T.; Arae, S.; Sugiura, M.; Nakajima, M. Mechanistic Investigations of Chiral Lithium Binaphtholate Catalysis for Asymmetric Aldol–Tishchenko Reaction of α‑Fluoroarylketones . J. Org. Chem. 2024, 89, 17101–17114. (DOI: 10.1021/acs.joc.4c01404)
Nakanishi, Riko; Kurauchi, Yuki; Kotani, Shunsuke; Hitora-Imamura, Natsuko; Seki, Takahiro; Katsuki, Hiroshi. Structurally distinct Nurr1 ligands exhibit different pharmacological characteristics in regulating inflammatory responses of microglial BV-2 cells. Biological & Pharmaceutical Bulletin 2024, 47, (11), 1937–1945. DOI
Kinoshita, Keita; Motomura, Kensuke; Ushida, Keisuke; Hirata, Yuma; Konno, Ayumu; Hirai, Hirokazu; Kotani, Shunsuke; Hitora-Imamura, Natsuko; Kurauchi, Yuki; Seki, Takahiro; Katsuki, Hiroshi. Nurr1 overexpression in the primary motor cortex alleviates motor dysfunction induced by intracerebral hemorrhage in the striatum in mice. Neurotherapeutics 2024, 21, (4), e00370. DOI
Arae, S.; Shimoda, Y.; Kuwajima, M.; Kotani, S.; Nakajima, M. Three- and Seven-membered Annulenones as a Lewis Base Catalyst for Enantioselective meso-Epoxide Opening . Adv. Synth. Catal. 2024, e202401186. (DOI: 10.1002/adsc.202401186)

2023

El-Desoky, Ahmed H.; Asano, Toshifumi; Maeyama, Yuka; Kato, Hikaru; Hitora, Yuki; Goto, Eishu; Kotani, Shunsuke; Nakajima, Makoto; Tsukamoto, Sachiko. Arteperoxides A-C, tris-normonoterpene-sesquiterpene conjugates with peroxide-bridges from Artemisia judaica exhibiting antiosteoclastogenic activity. Phytochemistry (Elsevier) 2023, 206, 113548. DOI
Sasaki, Ryoko; Suico, Mary Ann; Chosa, Keisuke; Teranishi, Yuriko; Sato, Takashi; Kagami, Asuka; Kotani, Shunsuke; Kato, Hikaru; Hitora, Yuki; Tsukamoto, Sachiko; Yamashita, Tomohiro; Yokoyama, Takeshi; Mizuguchi, Mineyuki; Kai, Hirofumi; Shuto, Tsuyoshi. Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors. Journal of Pharmacological Sciences (Amsterdam, Netherlands) 2023, 151, (1), 54–62. DOI
Kuwazuru, Jun; Suico, Mary Ann; Omachi, Kohei; Kojima, Haruka; Kamura, Misato; Kaseda, Shota; Kawahara, Teppei; Hitora, Yuki; Kato, Hikaru; Tsukamoto, Sachiko; Wada, Mikiyo; Asano, Toshifumi; Kotani, Shunsuke; Nakajima, Makoto; Misumi, Shogo; Sannomiya, Yuya; Horizono, Jun; Koyama, Yuimi; Owaki, Aimi; Shuto, Tsuyoshi; Kai, Hirofumi. CyclosporinA Derivative as Therapeutic Candidate for Alport Syndrome by Inducing Mutant Type IV Collagen Secretion.. Kidney360 2023, 4, (7), 909–917. DOI
Harada, N.; Asano, T.; Sugiura, M.; Kotani, S.; Nakajima, M. Lithium binaphtholate‑catalyzed asymmetric Michael reaction of acrylamides . Chem. Pharm. Bull. 2023, 71, 792–797. (DOI: 10.1248/cpb.c23-00435)
Yoshiwara, Y.; Kotani, S.; Nakajima, M. Enantioselective and Chemoselective Phosphine Oxide‑catalyzed Aldol Reaction of N‑Unprotected Cyclic Carboxyimides . Chem. Eur. J. 2023, e202203506. (DOI: 10.1002/chem.202203506)

2022

Nakajima, M.; Kotani, S.; Sugiura, M. Enantioselective Epoxide Opening . Org. React. 2022, 110, 655–902. (DOI: 10.1002/0471264180.or110.02)
El‑desoky, A. H. H.; Eguchi, K.; Kishimoto, N.; Asano, T.; Kato, H.; Hitora, Y.; Kotani, S.; Nakamura, T.; Tsuchiya, S.; Kawahara, T.; Watanabe, M.; Wada, M.; Nakajima, M.; Watanabe, T.; Misumi, S.; Tsukamoto, S. Isolation, Synthesis, and Structure‑Activity Relationship Study on Daphnane and Tigliane Diterpenes as HIV Latency‑Reversing Agents . J. Med. Chem. 2022, 65, 3460–3472. (DOI: 10.1021/acs.jmedchem.1c01973)
Kinoshita, K.; Yoshimizu, A.; Ichihara, Y.; Ushida, K.; Kotani, S.; Kurauchi, Y.; Seki, T.; Katsuki, H. A Nurr1 ligand C‑DIM12 attenuates brain inflammation and improves functional recovery after intracerebral hemorrhage in mice . Scientific Reports 2022, 12, 11009. (DOI: 10.1038/s41598-022-15178-7)

2021

Kobashigawa, Yoshihiro; Ohara, Toshiya; Morita, Kosuke; Toyota, Yuya; Nakamura, Teruya; Kotani, Shunsuke; Arimori, Takao; Yamauchi, Soichiro; Liu, Chenjiang; Kitazaki, Masaya; Wakeyama-Miyazaki, Yukari; Suwa, Yoshiaki; Uchida-Kamekura, Makiyo; Fukuda, Natsuki; Sato, Takashi; Nakajima, Makoto; Takagi, Junichi; Yamagata, Yuriko; Morioka, Hiroshi. Molecular recognition of a single-chain Fv antibody specific for GA-pyridine, an advanced glycation end-product (AGE), elucidated using biophysical techniques and synthetic antigen analogs. Journal of Biochemistry 2021, 170, (3), 379–387. DOI
Kobashigawa, Y.; Ohara, T.; Morita, K.; Toyota, Y.; Nakamura, T.; Kotani, S.; Arimori, T.; Yamauchi, S.; Liu, C.; Kitazaki, M.; Wakayama‑Miyazaki, Y.; Suwa, Y.; Uchida‑Kamekura, M.; Fukuda, N.; Sato, T.; Nakajima, M.; Takagi, J.; Yamagata, Y.; Morioka, H. Molecular recognition of a single‑chain Fv antibody specific for GA‑pyridine… J. Biochem. 2021, 170, 379–387.
Kotani, S.; Tashima, Y.; Tanaka, H.; Aoki, S.; Nakajima, M. Chiral Phosphine Oxide‑Catalyzed Enantioselective Ring Opening of Oxetanes . Heterocycles 2021, 103, 1048–1056. (DOI: 10.3987/COM-20-S(K)
Sugiura, M.; Kotani, S.; Nakajima, M.. Catalysis by silicon species. RSC Catalysis Series 2021, 40, 309–333.
Sugiura, M.; Kotani, S.; Nakajima, M. Catalysis with Earth‑abundant Elements; CHAPTER 11: Catalysis by Silicon Species. RSC Catalysis Series 2021, 40, 309–333.
Kai, Hirofumi; Shuto, Tsuyoshi; Suico, Mary Ann; Tsukamoto, Sachiko; Misumi, Shogo; Kawahara, Teppei; Hitora, Yuki; Kato, Hikaru; Kotani, Shunsuke; Araki, Kimi. Drug for curative therapy of intractable hereditary renal alport syndrome contaiing cyclophilin D inhibitor. 2021, (WO2021049633).

2020

Itoi, Hiroyuki; Kotani, Shunsuke; Tanabe, Yuichiro; Kasai, Yuto; Suzuki, Ryutaro; Miyaji, Masahiro; Iwata, Hiroyuki; Ohzawa, Yoshimi. Study of the mesopore size effect on the electrochemical capacitor behaviors of mesoporous carbon/quinone derivative hybrids. Electrochimica Acta 2020, 362, 137119. DOI
Kotani, Shunsuke; Nakajima, Makoto. Asymmetric cross-aldol reactions between two carbonyl compounds catalyzed by chiral phosphine oxides. Yuki Gosei Kagaku Kyokaishi 2020, 78, (12), 1163–1173.
Boateng, A.; Harada, T.; Ashikari, Y.; Nakajima, M.; Sugiura, M. Synthesis of conjugated multiunsaturated thioesters via one‑pot TiCl4‑promoted aldol condensation . Tetrahedron Lett. 2020, 61, 152280. (DOI: 10.1016/j.tetlet.2020.152280)
Kotani, S.; Nakajima, M. Recent Advances in Asymmetric Phosphine Oxide Catalysis . Tetrahedron Lett. 2020, 61, 151421. (DOI: 10.1016/j.tetlet.2019.151421)
Yoshimitsu, T.; Kuboyama, Y.; Nishiguchi, S.; Nakajima, M.; Sugiura, M. O‑Monoacyltartaric Acid/(Thio)urea Cooperative Organocatalysis for Enantioselective Conjugate Addition of Boronic Acid . Org. Lett. 2020, 22, 3780–3784. (DOI: 10.1021/acs.orglett.0c00981)
Kotani, S.; Hanamure, T.; Mori, Y.; Nakajima, M. Phosphine‑oxide‑catalyzed Enantioselective Cross‑aldol Reaction of Aldehydes with Trichlorosilane as Lewis Acid Promoter . ChemCatChem 2020, 12, 4780–4783. (DOI: 10.1002/cctc.202000914)
Oniki, Kentaro; Kawakami, Taisei; Nakashima, Azusa; Miyata, Keishi; Watanabe, Takehisa; Fujikawa, Haruka; Nakashima, Ryunosuke; Nasu, Aoi; Eto, Yuka; Takahashi, Noriki; Nohara, Hirofumi; Suico, Mary Ann; Kotani, Shunsuke; Obata, Yui; Sakamoto, Yuki; Seguchi, Yuri; Saruwatari, Junji; Imafuku, Tadashi; Watanabe, Hiroshi; Maruyama, Toru; Kai, Hirofumi; Shuto, Tsuyoshi. Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions. Scientific Reports 2020, 10, (1), 4313. DOI

2019

Sugiura, M.; Ashikari, Y.; Takahashi, Y.; Yamaguchi, K.; Kotani, S.; Nakajima, M. Lewis Base‑catalyzed Enantioselective Conjugate Reductions of β,β‑Disubstituted α,β‑Unsaturated Ketones with Trichlorosilane … J. Org. Chem. 2019, 84, 11458–11473. (DOI: 10.1021/acs.joc.9b01298)
Hashimoto, Y.; Michimuko, C.; Yamaguchi, K.; Nakajima, M.; Sugiura, M. Selective Monoacylation of Diols … J. Org. Chem. 2019, 84, 9313–9321. (DOI: 10.1021/acs.joc.9b00827)
Kotani, Shunsuke. Phosphine oxide-catalyzed asymmetric aldol reactions and double aldol reactions. Chemical & Pharmaceutical Bulletin 2019, 67, (6), 519–526. DOI
Sakamoto, M.; Kaneko, T.; Orito, Y.; Shimoda, Y.; Nakajima, M. Lithium Binaphtholate‑Catalyzed Michael Reaction of Malonates … Chem. Pharm. Bull. 2019, 67, 452–446. (DOI: 10.1248/cpb.c18-00993)
Asano, T.; Kotani, S.; Nakajima, M. Stereoselective Synthesis of 2‑Fluoro‑1,3‑diols via Lithium Binaphtholate‑catalyzed Aldol–Tishchenko Reaction . Org. Lett. 2019, 21, 4192–4196. (DOI: 10.1021/acs.orglett.9b01371)

2018

Kotani, S.; Yoshiwara, Y.; Ogasawara, M.; Sugiura, M.; Nakajima, M. Catalytic Enantioselective Aldol Reactions of Unprotected Carboxylic Acids under Phosphine Oxide Catalysis . Angew. Chem. Int. Ed. 2018, 57, 15877–15881. (DOI: 10.1002/anie.201810599)
Nakajima, M.; Watanabe, R.; Osakama, K.; Sakamoto, M.; Takemoto, D.; Kukita, K. Dramatic Enantioselectivity Reversal … Heterocycles 2018, 97, 708–711. (DOI: 10.3987/COM-18-S(T)

2017

Asano, Toshifumi; Moritani, Miyuki; Nakajima, Makoto; Kotani, Shunsuke. Chiral lithium binaphtholate for enantioselective amination of acyclic α-alkyl-β-keto esters: Application to the total synthesis of L-carbidopa. Tetrahedron 2017, 73, (41), 5975–5982. DOI
Kotani, Shunsuke; Hanamure, Takuya; Nozaki, Hirono; Sugiura, Masaharu; Nakajima, Makoto. Enantioselective chlorinative aldol reaction of α-substituted acroleins catalyzed by chiral phosphine oxides. Tetrahedron: Asymmetry 2017, 28, (2), 282–287. DOI
Sugiura, Masaharu; Kashiwagi, Takeru; Ito, Mai; Kotani, Shunsuke; Nakajima, Makoto. Stereoselective Synthesis of Nitrogen-Containing Compounds from Enamines. Journal of Organic Chemistry 2017, 82, (20), 10968–10979. DOI
Sugiura, M.; Kashiwagi, T.; Ito, M.; Kotani, S.; Nakajima, M. Stereoselective Synthesis of Nitrogen‑containing Compounds from Enamines. J. Org. Chem. 2017, 82, 10968–10979.
Ishikawa, Hayato; Nishino, Hiroshi; Nakajima, Makoto; Kotani, Shunsuke. The 2016 kumamoto earthquake; reconstruction and countermeasures. Yuki Gosei Kagaku Kyokaishi 2017, 75, (3), 259–263. DOI
Asano, T.; Moritani, M.; Nakajima, M.; Kotani, S. Chiral Lithium Binaphtholate… Tetrahedron 2017, 73, 5975–5982.
中島誠. ホスフィンオキシドを有機分子触媒とする不斉アルドール反応の開発. 化学工業 2017, 68, 66–72.
Alim, Nathan Ray; Miyazaki, Shiki; Shimoda, Yasushi; Sugiura, Masaharu; Nakajima, Makoto; Kotani, Shunsuke. Asymmetric aldol/vinylogous aldol/cyclization reaction using phosphine oxide catalysts. Chemical & Pharmaceutical Bulletin 2017, 65, (10), 989–993. DOI
Alim, N. R.; Miyazaki, S.; Shimoda, Y.; Sugiura, M.; Nakajima, M.; Kotani, S. Asymmetric Aldol/Vinylogous Aldol/Cyclization… Chem. Pharm. Bull. 2017, 65, 989–993.
Kotani, S.; Hanamure, T.; Nozaki, H.; Sugiura, M.; Nakajima, M. Enantioselective Chlorinative Aldol Reaction… Tetrahedron: Asymmetry 2017, 28, 282–287.
Kotani, Shunsuke; Kai, Kosuke; Sugiura, Masaharu; Nakajima, Makoto. Sequential Catalysis of Phosphine Oxide for Stereoselective Synthesis of Stereopentads. Organic Letters 2017, 19, (13), 3672–3675. DOI
Kotani, S.; Kai, K.; Sugiura, M.; Nakajima, M. Sequential Catalysis of Phosphine Oxide… Org. Lett. 2017, 19, 3672–3675.

2016

Kotani, Shunsuke; Asano, Toshifumi; Moritani, Miyuki; Nakajima, Makoto. Enantioselective amination of acyclic α-alkylated β-keto esters catalyzed by chiral lithium binaphtholate. Tetrahedron Letters 2016, 57, (37), 4217–4219. DOI
Kotani, S.; Miyazaki, S.; Kawahara, K.; Shimoda, Y.; Sugiura, M.; Nakajima, M. Stereoselective Synthesis of Highly Functionalized 2,3‑Dihydro‑4‑pyranones … Chem. Pharm. Bull. 2016, 64, 189–192. (DOI: 10.1248/cpb.c15-00806)
Kotani, S.; Asano, T.; Moritani, M.; Nakajima, M. Enantioselective Amination of Acyclic α‑Alkylated β‑Keto Esters… Tetrahedron Lett. 2016, 57, 4217–4219.
Sakamoto, M.; Kaneko, T.; Orito, Y.; Nakajima, M. Enantioselective Michael Addition of a Malonate Ester… Synlett 2016, 27, 2477–2780.
Osakama, K.; Nakajima, M. Asymmetric Direct 1,2‑Addition of Aryl Grignard Reagents to Aryl Alkyl Ketones . Org. Lett. 2016, 18, 236–239. (DOI: 10.1021/acs.orglett.5b03379)
Kotani, S.; Kai, K.; Shimoda, Y.; Hu, H.; Gao, S.; Sugiura, M.; Ogasawara, M.; Nakajima, M. Concise Asymmetric Construction of C2‑Symmetric 1,9‑Diarylnonanoids … Chem. Asian J. 2016, 11, 376–379. (DOI: 10.1002/asia.201501080)
Enoki, Yuki; Watanabe, Hiroshi; Arake, Riho; Sugimoto, Ryusei; Imafuku, Tadashi; Tominaga, Yuna; Ishima, Yu; Kotani, Shunsuke; Nakajima, Makoto; Tanaka, Motoko; Matsushita, Kazutaka; Fukagawa, Masafumi; Otagiri, Masaki; Maruyama, Toru. Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1. Scientific Reports 2016, 6, 32084. DOI
Enoki, Y.; Watanabe H.; Arake, R.; Sugimoto, R.; Imafuku, T.; Tominaga, Y.; Ishima, Y.; Kotani, S.; Nakajima, M.; Tanaka, M.; Matsushita, K.; Fukagawa, M.; Otagiri, M.; Maruyama, T. Indoxyl Sulfate Potentiates Skeletal Muscle Atrophy… Sci. Rep. 2016, 6, 32084.

2015

Ishima, Y.; Narisoko, T.; Kragh‑Hansen, U.; Kotani, S.; Nakajima, M.; Otagiri, M.; Maruyama, T. Nitration of Indoxyl Sulfate … Biochem. Biophys. Res. Commun. 2015, 465, 481–487. (DOI: 10.1016/j.bbrc.2015.08.043)
Kotani, Shunsuke; Sakamoto, Midori; Osakama, Kazuki; Nakajima, Makoto. A Sterically Congested α-Cyanoamine as a Cyanating Reagent: Cyanation of Acetals and Orthoesters. European Journal of Organic Chemistry 2015, 2015, (30), 6606–6609. DOI
Ohura, Kayoko; Nakada, Yuichiro; Kotani, Shunsuke; Imai, Teruko. Design of fexofenadine prodrugs based on tissue-specific esterase activity and their dissimilar recognition by p-glycoprotein. Journal of Pharmaceutical Sciences 2015, 104, (9), 3076–3083. DOI
Sugiura, M.; Ashigari, Y.; Nakajima, M. One‑pot Synthesis of β,β‑Disubstituted α,β‑Unsaturated Carbonyl Compounds … J. Org. Chem. 2015, 80, 8830–8835. (DOI: 10.1021/acs.joc.5b01217)
Sugiura, M.; Ishikawa, W.; Kuboyama, Y.; Nakajima, M. Conjugate Addition of Diboron Catalyzed by O‑Monoacyltartaric Acid . Synthesis 2015, 47, 2265–2269. (DOI: 10.1055/s-0034-1378835)
Kotani, S.; Sakamoto, M.; Osakama, K.; Nakajima, M. Tertiary Amine as a Nucleophile Carrier… Eur. J. Org. Chem. 2015, 30, 6606–6609.
Kotani, Shunsuke; Moritani, Miyuki; Nakajima, Makoto. Chiral Lithium Binaphtholate for Enantioselective Michael Addition of Acyclic α-Alkyl-β-Keto Esters to Vinyl Ketones. Asian Journal of Organic Chemistry 2015, 4, (7), 616–618. DOI
Kotani, S.; Moritani, M.; Nakajima, M. Chiral Lithium Binaphtholate… Asian J. Org. Chem. 2015, 4, 616–618.
Wada, Yusuke; Lee, Haejoo; Hoshino, Yu; Kotani, Shunsuke; Shea, Kenneth J.; Miura, Yoshiko. Design of multi-functional linear polymers that capture and neutralize a toxic peptide: a comparison with cross-linked nanoparticles. Journal of Materials Chemistry B: Materials for Biology and Medicine 2015, 3, (8), 1706–1711. DOI
Watanabe, Hiroshi; Miyamoto, Yohei; Enoki, Yuki; Ishima, Yu; Kadowaki, Daisuke; Kotani, Shunsuke; Nakajima, Makoto; Tanaka, Motoko; Matsushita, Kazutaka; Mori, Yoshitaka; Kakuta, Takatoshi; Fukagawa, Masafumi; Otagiri, Masaki; Maruyama, Toru. p-Cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress. Pharmacology Research & Perspectives 2015, 3, (1), n/a. DOI

2014

Ito, Mai; Kashiwagi, Takeru; Kotani, Shunsuke; Nakajima, Makoto; Sugiura, Masaharu. Imino ene-type reaction of enamines with N-sulfonylimines and application to diastereoselective synthesis of N-sulfonyl-1,3-diamines. Tetrahedron Letters 2014, 55, (30), 4082–4085. DOI
Kashiwagi, Takeru; Kotani, Shunsuke; Nakajima, Makoto; Sugiura, Masaharu. Diastereoselective synthesis of 1,3-diamines by a domino reaction of imines, enamines, and trichlorosilane. Tetrahedron Letters 2014, 55, (11), 1924–1926. DOI
Kotani, Shunsuke; Kukita, Kenji; Tanaka, Kana; Ichibakase, Tomonori; Nakajima, Makoto. Lithium Binaphtholate-Catalyzed Asymmetric Addition of Lithium Acetylides to Carbonyl Compounds. Journal of Organic Chemistry 2014, 79, (11), 4817–4825. DOI
Osaka, Y.; Onimaru, H.; Kotani, S.; Kashiwagi, M.; Morisaki, H.; Takeda, J.. The effects of doxapram on medullary respiratory neurones in brainstem-spinal cord preparations from newborn rats. Anaesthesia 2014, 69, (5), 468–475. DOI
Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Enantioselective Double Aldol Reactions Involving the Sequential Activation of Silicon Tetrachloride by Chiral Phosphine Oxides. Synlett 2014, 25, (5), 631–640. DOI
Watanabe, Hiroshi; Sakaguchi, Yoshiaki; Sugimoto, Ryusei; Kaneko, Ken-ichi; Iwata, Hiroshi; Kotani, Shunsuke; Nakajima, Makoto; Ishima, Yu; Otagiri, Masaki; Maruyama, Toru. Human organic anion transporters function as a high-capacity transporter for p-cresyl sulfate, a uremic toxin. Clinical and Experimental Nephrology 2014, 18, (5), 814–820. DOI
Watanabe, H.; Sakaguchi, Y.; Sugimoto, R.; Kaneko, K.; Iwata, H.; Kotani, S.; Nakajima, M.; Ishima, Y.; Otagiri, M.; Maruyama, T. Human Organic Anion Transporters… Clin. Exp. Nephrol. 2014, 18, 814–820.
Kotani, Shunsuke; Aoki, Shohei; Sugiura, Masaharu; Ogasawara, Masamichi; Nakajima, Makoto. Phosphine Oxide-Catalyzed Enantioselective Intramolecular Aldol Reaction via Regioselective Enolization of Unsymmetrical Diketones with Tetrachlorosilane. Organic Letters 2014, 16, (18), 4802–4805. DOI

2013

Kotani, Shunsuke; Ito, Masaya; Nozaki, Hirono; Sugiura, Masaharu; Ogasawara, Masamichi; Nakajima, Makoto. Enantioselective Morita-Baylis-Hillman reaction catalyzed by a chiral phosphine oxide. Tetrahedron Letters 2013, 54, (48), 6430–6433. DOI
Kotani, Shunsuke; Furusho, Haruka; Sugiura, Masaharu; Nakajima, Makoto. Facile synthesis of chiral 1,2-chlorohydrins via the ring-opening of meso-epoxides catalyzed by chiral phosphine oxides. Tetrahedron 2013, 69, (14), 3075–3081. DOI
Watanabe, Hiroshi; Miyamoto, Yohei; Honda, Daisuke; Tanaka, Hisae; Wu, Qiong; Endo, Masayuki; Noguchi, Tsuyoshi; Kadowaki, Daisuke; Ishima, Yu; Kotani, Shunsuke; Nakajima, Makoto; Kataoka, Keiichiro; Kim-Mitsuyama, Shokei; Tanaka, Motoko; Fukagawa, Masafumi; Otagiri, Masaki; Maruyama, Toru. p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase. Kidney International 2013, 83, (4), 582–592. DOI
Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Structure constructions utilizing continuous aldol reactions: deployment to stereoselective synthesis of polyols. Kagaku (Kyoto, Japan) 2013, 68, (12), 64–65.
Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Structure constructions utilizing continuous aldol reactions: deployment to stereoselective synthesis of polyols. Kagaku (Kyoto, Japan) 2013, 68, (12), 64–65.
Ogasawara, Masamichi; Kotani, Shunsuke; Nakajima, Hikaru; Furusho, Haruka; Miyasaka, Mitsuru; Shimoda, Yasushi; Wu, Wei-Yi; Sugiura, Masaharu; Takahashi, Tamotsu; Nakajima, Makoto. Atropisomeric Chiral Dienes in Asymmetric Catalysis: C2-Symmetric (Z,Z)-2,3-Bis[1-(diphenylphosphinyl)ethylidene|tetralin as a Highly Active Lewis Base Organocatalyst. Angewandte Chemie, International Edition 2013, 52, (51), 13798–13802. DOI
Shimoda, Yasushi; Kubo, Tatsunori; Sugiura, Masaharu; Kotani, Shunsuke; Nakajima, Makoto. Stereoselective synthesis of multiple stereocenters by using a double aldol reaction. Angewandte Chemie, International Edition 2013, 52, (12), 3461–3464. DOI
Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Enantioselective Aldol Reactions Catalyzed by Chiral Phosphine Oxides. Chemical Record 2013, 13, (4), 362–370. DOI

2012

Osakama, Kazuki; Sugiura, Masaharu; Nakajima, Makoto; Kotani, Shunsuke. Enantioselective reductive aldol reaction using tertiary amine as hydride donor. Tetrahedron Letters 2012, 53, (32), 4199–4201. DOI
Ichibakase, Tomonori; Kaneko, Tetsuya; Orito, Yuya; Kotani, Shunsuke; Nakajima, Makoto. Construction of quaternary carbon centers by a base-catalyzed enantioselective aldol reaction and related reactions of trimethoxysilyl enol ethers. Tetrahedron 2012, 68, (22), 4210–4224. DOI
Kotani, S.; Nakajima, M.. C-X bond formation: organocatalytic enantioselective halogenation of meso epoxides. Comprehensive Chirality 2012, 506. DOI
Aoki, Shohei; Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Trichlorosilyl triflate-mediated enantioselective directed cross-aldol reaction between ketones using a chiral phosphine oxide as an organocatalyst. Chemical Communications (Cambridge, United Kingdom) 2012, 48, (44), 5524–5526. DOI
Watanabe, Hiroshi; Noguchi, Tsuyoshi; Miyamoto, Yohei; Kadowaki, Daisuke; Kotani, Shunsuke; Nakajima, Makoto; Miyamura, Shigeyuki; Ishima, Yu; Otagiri, Masaki; Maruyama, Toru. Interaction between two sulfate-conjugated uremic toxins, p-cresyl sulfate and indoxyl sulfate, during binding with human serum albumin. Drug Metabolism & Disposition 2012, 40, (7), 1423–1428. DOI
Ohmaru, Yusuke; Sato, Norimasa; Mizutani, Makoto; Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Synthesis of aryl group-modified DIOP dioxides (Ar-DIOPOs) and their application as modular Lewis base catalysts. Organic & Biomolecular Chemistry 2012, 10, (23), 4562–4570. DOI

2011

Kashiwagi, Takeru; Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Synthesis of γ-amino alcohols from aldehydes, enamines, and trichlorosilane using Lewis base catalysts. Tetrahedron 2011, 67, (2), 531–539. DOI
Kotani, Shunsuke; Aoki, Shohei; Sugiura, Masaharu; Nakajima, Makoto. Trichlorosilyl triflate for enantioselective direct-type aldol reaction with chiral phosphine oxide. Tetrahedron Letters 2011, 52, (22), 2834–2836. DOI
Tanaka, Kana; Kukita, Kenji; Ichibakase, Tomonori; Kotani, Shunsuke; Nakajima, Makoto. Lithium acetylides as alkynylating reagents for the enantioselective alkynylation of ketones catalyzed by lithium binaphtholate. Chemical Communications (Cambridge, United Kingdom) 2011, 47, (19), 5614–5616. DOI
Miyamoto, Yohei; Watanabe, Hiroshi; Noguchi, Tsuyoshi; Kotani, Shunsuke; Nakajima, Makoto; Kadowaki, Daisuke; Otagiri, Masaki; Maruyama, Toru. Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney. Nephrology, Dialysis, Transplantation 2011, 26, (8), 2498–2502. DOI
Shimoda, Yasushi; Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Enantioselective Double Aldol Reaction Catalyzed by Chiral Phosphine Oxide. Chemistry - A European Journal 2011, 17, (29), 7992. DOI
Kotani, Shunsuke; Osakama, Kazuki; Sugiura, Masaharu; Nakajima, Makoto. A Tertiary Amine as A Hydride Donor: Trichlorosilyl Triflate-mediated Conjugate Reduction of Unsaturated Ketones. Organic Letters 2011, 13, (15), 3968–3971. DOI

2010

Oh, Young Seon; Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Development of chiral dinitrones as modular Lewis base catalysts: asymmetric allylation of aldehydes with allyltrichlorosilanes. Tetrahedron: Asymmetry 2010, 21, (15), 1833–1835. DOI
Aoki, Shohei; Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. DMAP-catalyzed cyanation of aldehydes and ketones with ethyl cyanoformate. Tetrahedron Letters 2010, 51, (27), 3547–3549. DOI
Nakamura, Yoshitaka; Burke, Anthony M.; Kotani, Shunsuke; Ziller, Joseph W.; Rychnovsky, Scott D.. Total Synthesis of (-)-Lycoperine A. Organic Letters 2010, 12, (1), 72–75. DOI
Sugiura, Masaharu; Sato, Norimasa; Sonada, Yuko; Kotani, Shunsuke; Nakajima, Makoto. Diastereo- and enantioselective reductive aldol reaction with trichlorosilane using chiral Lewis bases as organocatalysts. Chemistry - An Asian Journal 2010, 5, (3), 478–481. DOI

2009

Kotani, Shunsuke; Shimoda, Yasushi; Sugiura, Masaharu; Nakajima, Makoto. Novel enantioselective direct aldol-type reaction promoted by a chiral phosphine oxide as an organocatalyst. Tetrahedron Letters 2009, 50, (32), 4602–4605. DOI
Shimoda, Yasushi; Tando, Teppei; Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. Enantioselective aldol reaction of silyl ketene acetals promoted by a Lewis base-activated Lewis acid catalyst. Tetrahedron: Asymmetry 2009, 20, (12), 1369–1370. DOI

2008

Nakanishi, Kyoko; Kotani, Shunsuke; Sugiura, Masaharu; Nakajima, Makoto. First asymmetric Abramov-type phosphonylation of aldehydes with trialkyl phosphites catalyzed by chiral Lewis bases. Tetrahedron 2008, 64, (27), 6415–6419. DOI
Sugiura, Masaharu; Sato, Norimasa; Kotani, Shunsuke; Nakajima, Makoto. Lewis base-catalyzed conjugate reduction and reductive aldol reaction of α,β-unsaturated ketones using trichlorosilane. Chemical Communications (Cambridge, United Kingdom) 2008, (36), 4309–4311. DOI

2007

Kotani, Shunsuke; Hashimoto, Shunichi; Nakajima, Makoto. Chiral phosphine oxide BINAPO as a Lewis base catalyst for asymmetric allylation and aldol reaction of trichlorosilyl compounds. Tetrahedron 2007, 63, (15), 3122–3132. DOI
Kida, A.; Kakihana, K.; Kotani, S.; Kurosu, T.; Miura, O.. Glycogen synthase kinase-3β and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells. Oncogene 2007, 26, (46), 6630–6640. DOI

2006

Kotani, S.; Yamauchi, T.; Teramoto, T.; Ogura, H.. Pharmacological evidence of cholinergic involvement in adult hippocampal neurogenesis in rats. Neuroscience (San Diego, CA, United States) 2006, 142, (2), 505–514. DOI
Kotani, Shunsuke; Hashimoto, Shunichi; Nakajima, Makoto. Enantioselective aldol reactions of trichlorosilyl enol ethers catalyzed by the chiral phosphine oxide BINAPO. Synlett 2006, (7), 1116–1118. DOI

2005

Nakajima, Makoto; Kotani, Shunsuke; Ishizuka, Tadao; Hashimoto, Shunichi. Chiral phosphine oxide BINAPO as a catalyst for enantioselective allylation of aldehydes with allyltrichlorosilanes. Tetrahedron Letters 2005, 46, (1), 157–159. DOI
Tokuoka, Eisuke; Kotani, Shunsuke; Matsunaga, Hirofumi; Ishizuka, Tadao; Hashimoto, Shunichi; Nakajima, Makoto. Asymmetric ring opening of meso-epoxides catalyzed by the chiral phosphine oxide BINAPO. Tetrahedron: Asymmetry 2005, 16, (14), 2391–2392. DOI