原著論文 - 業績 | 熊本大学大学院生命科学研究部　環境分子保健学分野

熊本大学
大学院生命科学研究部
環境分子保健学分野

〒862-0973
熊本市中央区大江本町5-1

misumi(*)kumamoto-u.ac.jp
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Honda I, Araki K, Honda S, Soeda F, Shin MC, Misumi S, Yamamura KI, Takahama K.
Deletion of GIRK2 subunit containing GIRK channels of neurons expressing dopamine transporter decrease immobility time on forced swimming in mice.
Neurosci Lett. (2018) 665:140-146.

Zhou JR, Shirasaki T, Soeda F, Takahama K.
The effects of suplatast tosilate on acutely dissociated sensory and paratracheal ganglia neurons.
Am J Physiol Lung Cell Mol Physiol. (2016) 311;L770-L778
Soeda F, Fujieda Y, Kinoshita M, Shirasaki T, Takahama K.
Centrally acting non-narcotic antitussives prevent hyperactivity in mice: Involvement of GIRK channels.
Pharmacol. Biochem. Behav. (2016) 16;144:26-32.
Kawaura K, Ogata Y, Honda S, Soeda F, Shirasaki T, Takahama K.
Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats.
Behav. Brain. Res. (2016) 1;302:269-78.

Hamao K, Kawaura K, Soeda F, Hamasaki R, Shirasaki T, Takahama K.
Tipepidine increases dopamine level in the nucleus accumbens without methamphetamine-like behavioral sensitization.
Behav. Brain. Res. (2015) 1;284:118-24.
Zhou JR, Syono R, Fukumi S, Kimoto K, Shirasaki T, Soeda F, Takahama K.
Novel antitussive effect of suplatast tosilate in guinea pigs.
Pharmacology. (2015) 95(1-2):36-41.

Zhou JR, Shirasaki T, Soeda F, Takahama K.
Cholinergic EPSCs and their potentiation by bradykinin in single paratracheal ganglion neurons attached with presynaptic boutons.
J. Neurophysiol. (2014) 15;112(4):933-41.
Soeda F, Hirakawa E, Inoue M, Shirasaki T, Takahama K.
Cloperastine rescues impairment of passive avoidance response in mice prenatally exposed to diethylstilbestrol. Environ. Toxicol. (2014) 29(2): 216-225.
Akaike N, Ito Y, Ogawa SK, Maeda M, Wakita M, Takahama K, Noguchi T, Kamei S, Hamamoto T, Umehashi M, Maeda H.
Potent cough suppression by physiologically active substance in human plasma. Gen. Physiol. Biophys. (2014) 33(2):145-55.

Kawahara R, Soeda F, Kawaura K, Honda S, Miki R, Noguchi T, Shirasaki T, Takahama K.
Effect of tipepidine with novel antidepressant-like action on c-fos-like protein expression in rat brain. Brain Res. (2013) 1513: 135-142.
Hamasaki R, Shirasaki T, Soeda F, Takahama K.
Tipepidine activates VTA dopamine neuron via inhibiting dopamine D₂ receptor-mediated inward rectifying K⁺ current. Neuroscience (2013) 252: 24-34.
Somekawa-Kondo T, Yamaguchi K, Ishitsuka Y, Ito S, Tanaka K, Irikura M, Moriuchi H, Takahama K, Ando Y, Yamazaki T, Irie T.
Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury under low tidal volume hypoxic conditions in guinea-pigs. J. Pharm. Pharmacol. (2013) 65(1): 102-114.

Kawaura K, Miki R, Urashima Y, Kawahara R, Soeda F, Shirasaki T, Takahama K.
Pharmacological mechanisms of antidepressant-like effect of tipepidine in the forced swimming test. Behav. Brain Res. (2012) 226(2): 381-385.
Takahama K.
Multiple pharmacological actions of centrally acting antitussives--Do they target G protein-coupled inwardly rectifying K⁺ (GIRK) channels? J. Pharmacol. Sci. (2012) 120(3): 146-151.

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