Department of Bioorganic Medicinal Chemistry

Division Advanced Biomedical Sciences
Great Department Molecular and Grenomic Pharmacy
Website http://www.pharm.kumamoto-u.ac.jp/Labs/gosei/main.html
Staff
Professor Masami Ohtsuka
motsuka@gpo.kumamoto-u.ac.jp
Associate professor Tadashi Ohkawara
okawara@gpo.kumamoto-u.ac.jp
Instructor Yoshinari Okamoto
okamoto@gpo.kumamoto-u.ac.jp
Research theme


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Calcium signaling pathway and inositol phosphates
Our research projects are design, synthesis, and biological evaluation of;
  1. inositol phosphates and other molecules that target the intracellular signaling pathway.
  2. anti-cancer drugs based on the molecular target concept, i.e., inhibitors of farnesyltransferase or topoisomerase.
  3. man-made molecules that target DNA, i. e., peptide nucleic acids and DNA-cleaving molecules.
  4. conophylline and other biologically active natural products.